An Agilent HP-3D capillary electrophoresis system is coupled with an Agilent 1100 Series LC/MSD SL mass spectrometer with an ion trap as analyzer (50-2200 m/z). The Agilent coaxial sheath-liquid sprayer is used for the electrospray interface and the sheat liquid is delivered by a PU-2085 Jasco high pressure pump equipped with a splitter 1:100.