N Concordance 1 ients then receive 3 cycles of adjuvant methotrexate/vinblastine/cisplatin che 2 se following exposure to the antifolate methotrexate (MTX), suggesting that MTX 3 articularly the antimetabolites such as methotrexate or fluorouracil, cause only 4 HFR-ricin cytotoxicity was inhibited by methotrexate, a DHFR inhibitor stabilizi 5 courses of antimetabolite chemotherapy (methotrexate/fluorouracil) followed by 6 rgh, found that CMF (cyclophosphamide, methotrexate, fluorouracil) produced few 7 d the combination of intermediate-dose methotrexate, bleomycin, doxorubicin, c 8 (four 1.0 mg/kg doses of intramuscular methotrexate alternated with 0.1 mg/kg o 9 diation in combination with intrathecal methotrexate. Cranial irradiation does p 10 e on days 1 through 14 and intravenous methotrexate and fluorouracil on days 1 11 vs. neoadjuvant chemotherapy with MVAC (methotrexate/vinblastine/doxorubicin/ci 12 and in vivo percutaneous absorption of methotrexate and edatrexate through hair 13 patient was treated with two courses of methotrexate, which did not affect her h 14 disease, low-dose IFN or low-dose oral methotrexate may be added. The three cla 15 rial. Of 51 patients allocated systemic methotrexate, 42 (82%) were successfully 16 ement In vitro transport resistance to methotrexate demonstrated by bone marrow