Generated by OntoTerm. Updated: 28/08/2002 3:23:28

ALKYLATING-DRUG


subject field: medicine: drugs
origination date: 17/12/2001
originator: Mercedes
input date: 17/12/2001
inputter: Arianne
check date: 25/02/2002
checker: Pamela

Conceptual Structures
ISAANTINEOPLASTIC-AGENT
SUBCLASSESAMSACRINE
BUSULFAN
CARBOPLATIN
CARMUSTINE
CHLORAMBUCIL
CHLOROZOTOCIN
CISPLATIN
CLOMESONE
CYANOMORPHOLINO-ADR
CYCLODISONE
CYCLOPHOSPHAMIDE
DIANHYDROGALACTITOL
DIAZIQUONE
ESTRAMUSTINE
FLUOROPAN
HEPSULFAM
IFOSFAMIDE
IPROPLATIN
L-ASPARAGINASE
LEUCINE
LOMUSTINE
MECHLORETAMINE
MELPHALAN
METHANESULFONATE
MITOZOLOMIDE
NITROGEN-MUSTARD
NITROSUREA
PIPERAZINE-ALKYLATOR
PIPERAZINEDIONE
PIPOBROMAN
PLATINATE
PROPANOL
SPIROHYDANTOIN-MUSTARD
TEROXIRONE
TETRAPLATIN-PLATINUM
THIOTEPA
TRETAMINE
URACIL-NITROGEN-MUSTARD
DESCENDANTSAMSACRINE
BUSULFAN
CARBOPLATIN
CARMUSTINE
CHLORAMBUCIL
CHLOROZOTOCIN
CISPLATIN
CLOMESONE
CYANOMORPHOLINO-ADR
CYCLODISONE
CYCLOPHOSPHAMIDE
DIANHYDROGALACTITOL
DIAZIQUONE
ESTRAMUSTINE
FLUOROPAN
HEPSULFAM
IFOSFAMIDE
IPROPLATIN
L-ASPARAGINASE
LEUCINE
LOMUSTINE
MECHLORETAMINE
MELPHALAN
METHANESULFONATE
MITOZOLOMIDE
NITROGEN-MUSTARD
NITROSUREA
PIPERAZINE-ALKYLATOR
PIPERAZINEDIONE
PIPOBROMAN
PLATINATE
PROPANOL
SPIROHYDANTOIN-MUSTARD
TEROXIRONE
TETRAPLATIN-PLATINUM
THIOTEPA
TRETAMINE
URACIL-NITROGEN-MUSTARD
ANCESTORSALL
ANTINEOPLASTIC-AGENT
DRUG
MATERIAL
OBJECT
PHARMACEUTICAL-MATERIAL
PHYSICAL-OBJECT
THERAPEUTICAL-MATERIAL


English
alkylating drugdefinition: anticancer drug which interferes with the division process of cancer cells, slowing or stopping their growth and reproduction. This drug is effective against breast and lung cancer, leukemias, and lymphomas, among others. It can occasionally cause sterility, and when used over a long period of time, it slightly increases the risk of leukemia. Some examples of alkylating drugs are Leukeran, Cytoxan, thiotepa and busulfan. (en)
number: mass
part of speech: noun
reliability code: 10
term type: main entry term
alkylating agentdefinition: Ref.cruzada con def de alkylating drug (en)
number: mass
part of speech: noun
reliability code: 10
term type: synonym

Spanish
fármaco alquilantedefinition: fármaco antineoplásico que produce lesiones estructurales que impiden la duplicación transcripción, síntesis de proteínas, mitosis, determinando de esta forma la muerte celular. Se utiliza, principalmente, en el tratamiento de linfomas, leucemias y carcinomas. Puede producir esterilidad en ambos sexos, amenorrea en la mujer y carcinogénesis. Entre los principales alquilantes son ciclofosfamida, cloranbucilo, thiotepa y busulfán. (es)
gender: masculine
number: mass
part of speech: noun
reliability code: 10
term type: main entry term
agente alquilantedefinition: Ref.cruzada con def de fármaco alquilante (es)
gender: masculine
number: mass
part of speech: noun
reliability code: 10
term type: synonym