Universidad de Granada
Facultad de Ciencias



Abstract: (Chemical Abstract 1997, 126:343769)


Conformational analysis using molecular mechanics and semiempirical calculations (AM1 and PM3) have been performed on 2'-halo derivatives of daunomycin. The numerical results obtained and those obtained from the electrostatic potential calculations have been used together in order to investigate theoretically the influence of the introduction of the halogen atom at C-2' position of the sugar moiety.

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