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• 1,3-dipolar cycloaditions between azido- and propargyl moities related with carbohydrates

• Neoglycoconjugates: Synthesis from propargyl glycosides

• Cyclodextrins: Chemical Modifications. Synthesis of glyco-cyclodextrins

Other topics

• Calixarenes: Chemical modifications. Synthesis of calix-sugars, calix-crowns and multicalixarenes

• Glycopyranosyl isothiocyanates: Synthesis and applications

• Cyclic sulfates sugars: Synthesis, Reactivity and Applications

• 1,5-Dialdehydes: Synthesis and Reactivity Knoevenagel Reaction Application to carbohydrates

• Branched Sugars at C-3: Synthesis and Reactivity

• Selective protection and acylations of carbohydrates

• Reactivity of glycals

• Pummerer Reaction. Application to carbohydrates

 

Research fundings

"Synthesis of multivalent neo-glycoconjugates by 1.3dipolar cycloadititions. Study of molecular recognition"

DGICYT. Proyect nº PB
November 2002- October 2005

“Synthesis of Multivalent Neoconjugates based on Cyclodextrins and Calixarenes for the Study of Carbohydrate-Lectin Interactions”

DGICYT. Proyect nº PB98-1320
December 1999 - October 2002

“Synthesis Of Cyclodextrin Templates And Scaffolds And Their Applications In The Synthesis of Cyclodextrinss Conjugated With Sugars, Peptides And Proteins”

DGICYT. Project nº PB95-1207-CO2
November1996 - October 1999

“Modified Cyclodextrins. New methods for the synthesis of acyclic and cyclic glycosylaminoglycans”

DGICYT. Project nº PB92-0936

January 1992 - December 1995.

"Synthetic Chemistry of Biologically and Medicinally Important Carbohydrates"

NATO. Grant for International collaboration in Research. CRG 890759

 

Collaborations

The group maintain or has maintained active collaborations with several groups

• Prof. . Vargas Berenguel. Universidad de Almería
• Prof. Sergio Castillon. Universidad Rovira i Virgili. Tarragona. Spain
• Prof. J. Manuel García Fernández. Instituto de Investigaciones Químicas. CSIC. Sevilla (Spain)
• Prof. Jesús Jiménez Barbero. Instituto de Química Orgánica. CSIC. Madrid (Spain)
• Prof. Rene Roy: Deartament of Chemistry. University of Otawa (Canada)
• Prof. Hans Baer. Deartament of Chemistry. University of Otawa (Canada)
• Prof.Luis Fermín Capitán Vallvey Departamento de Química Analítica (Universiy of Granada

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